A Specific Diplotype H1j/H2 of the MAPT Gene Could Be Responsible for Parkinson's Disease with Dementia.

Case Rep Genet · 2020 · PMC7732378 · PMID 33343949

Europe PMC DOI

hedged sentence

0.2770

closest p · 5.5× alpha

0.2770

boldest claim

The sentences

showed a trendp = 0.277not close (p > 0.1)

The comparison of the frequencies of the H1j/H2 diplotype between sporadic idiopathic PD (3/80) and control subjects (1/92) showed a trend of association since the odds ratio was 3.35 which remains still not significant (3.75 vs. 1.0%; OR, 3.55; 95% CI, 0.36–34.78; p = 0.277) due to the rarity of the diplotype and the small size of the samples.

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