showed a trendp = 0.068
29 One meta-analysis of trimodality treatment with surgery versus definitive CRT (concurrent or sequential not specified) showed a trend towards a survival benefit with trimodality treatment (HR 0.87; 95% CI 0.75–1.01; p = 0.068). 30 Guideline recommendations for stage III NSCLC There are a number of local and international guidelines providing recommendations on the treatment of stage III NSCLC. 15 , 24 , 31 There are some areas of consensus opinion including recommending definitive CRT in unresectable stage III NSCLC and other areas with less consensus.