KRAS Codon 12 Mutation is Associated with More Aggressive Invasiveness in Synchronous Metastatic Colorectal Cancer (mCRC): Retrospective Research.

When compared with all wild type, differences between NRAS mutation and clinical features did not reach statistical significance, BRAF mutation showed significant association with mucinous/rare histological subtypes, distant lymph node metastasis and multi-organ metastases in comparison with all wild type (P=0.026 and P=0.029, P=0.003, respectively).

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