Barely Significant
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A randomized controlled double-blind study of rotigotine on neuropsychiatric symptoms in de novo PD.

NPJ Parkinsons Dis · 2020 · PMC7738499 · PMID 33319786

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showed a trendno p-value reported
The Ardouin Scale of Behavior in PD showed a trend toward a reduction in apathy in the rotigotine group at 6 months although not significant (−1.15 ± 0.97, −53.6% under rotigotine, −0.67 ± 1.02, −27.7% under placebo, p = 0.1).

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