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Site-specific targeting of a light activated dCas9-KillerRed fusion protein generates transient, localized regions of oxidative DNA damage.

PLoS One · 2020 · PMC7746297 · PMID 33332350

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Extended exposure for 1hr at 20K Lux led to variable decreases in template integrity across multiple replicates, but these did not reach statistical significance ( Fig 4A ).

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