Impaired Brain Energy Metabolism: Involvement in Depression and Hypothyroidism.

Front Neurosci · 2020 · PMC7746780 · PMID 33343282

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did not reach statistical significanceno p-value reported

In the blood, both TSH and fT3 levels tended to be higher in the WKY rats than in control animals, and although these changes did not reach statistical significance, they suggested a weakening of the inhibitory effect of T3 on TSH secretion (i.e., the attenuation of the feedback mechanism regulating HPT axis activity).

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