Assessment of right ventricular sympathetic dysfunction in patients with arrhythmogenic right ventricular cardiomyopathy: An ¹²³I-metaiodobenzylguanidine SPECT/CT study.

There was a highly significant difference in the mean RV/M ratios between both groups (1.6 ± 0.3 vs. 2.0 ± 0.2, P = 0.001), with optimal cut-off for discrimination at 1.86 (88% sensitivity, 90% specificity, AUC 0.93).

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Results Planar Image Analysis The mean planar H/M ratios of the early and delayed images were slightly lower in the ARVC/D group as compared to the IVF reference group, but this difference did not reach statistical significance according to unpaired Student’s t -test (early 1.6 ± 0.2 vs. 1.8 ± 0.2, P = 0.196; delayed 1.5 ± 0.3 vs. 1.7 ± 0.2, P = 0.068); the WOR was non-significantly higher in the ARVC/D group (50% ± 14% vs. 42% ± 8%, P = 0.123) (representative images see Figure 2 top).

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