a significant trendP = 0.066
In addition, H-MR had a significant trend ( P = 0.066) to increase the crypt depth of the ileum compared to BD. 3.6 Intestinal barrier function Analyzed the mRNA expression levels of Claudin-1, Occludin and zonula occludens-1 ( ZO-1 ) in the small intestine were presented in Fig. 3 .