Dolutegravir in pregnant mice is associated with increased rates of fetal defects at therapeutic but not at supratherapeutic levels.

EBioMedicine · 2021 · PMC7753150 · PMID 33341441

Europe PMC DOI

hedged sentence

0.1600

closest p · 3.2× alpha

0.1600

boldest claim

The sentences

did not reach statistical significancep =0.16not close (p > 0.1)

The OR for NTDs was 6.92 (95%CI 0.38–127) for the 1x-DTG compared to control, which did not reach statistical significance ( p =0.16, by Fisher's exact test).

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