The K-M curve of time to first wrist fracture event showed a trend towards early separation between the ABL and PBO groups; this separation increased through the remainder of ACTIVE and was maintained with subsequent ALN treatment throughout ACTIVExtend, although there was no statistically significant difference between treatment groups.
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Forearm bone mineral density and fracture incidence in postmenopausal women with osteoporosis: results from the ACTIVExtend phase 3 trial.
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