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An IL-2-grafted antibody immunotherapy with potent efficacy against metastatic cancer.

Nat Commun · 2020 · PMC7755894 · PMID 33353953

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showed a trendno p-value reported
The optimal dose of NARA1leukin was determined to correspond to 0.5 μg hIL-2 equivalent, as higher doses did not further increase CD8 + T and NK cell expansion but showed a trend toward toxicity (Supplementary Fig. 1 ).

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