Prodrugs of γ-Alkyl-Modified Nucleoside Triphosphates: Improved Inhibition of HIV Reverse Transcriptase.

Angew Chem Int Ed Engl · 2020 · PMC7756582 · PMID 32379948

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a clear trendno p-value reported

Chemical Stability in Aqueous Phosphate Buffer (PBS, pH 7.3) In PBS, the half‐lives of γ‐(AB,alkyl)‐d4TTP prodrugs 6 were found to be between 94 h and 269 h without showing a clear trend.

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