Barely Significant
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The Number of Concomitant Drugs and the Safety of Direct Oral Anticoagulants in Routine Care Patients with Atrial Fibrillation.

TH Open · 2020 · PMC7758151 · PMID 33376941

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a clear trendno p-value reported
The adjusted HRs differed slightly among the strata but did not show a clear trend toward a benefit or harm of DOACs versus VKA with an increasing (or decreasing) number of concomitant drugs prescribed.

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