did not reach statistical significancep = 0.3127
Conversely, in the 24 patients whose relative ctDNA abundance was below or equal to the median (7 patients treated with chemotherapy, 17 patients treated with atezolizumab), patients treated with atezolizumab had a longer OS than in the chemotherapy arm in univariate analysis, although the difference did not reach statistical significance (HR atezolizumab arm = 0.55 (95% CI: 0.17–1.75) p = 0.3127; Figure 3 B).