Histone Carbonylation Is a Redox-Regulated Epigenomic Mark That Accumulates with Obesity and Aging.

Antioxidants (Basel) · 2020 · PMC7761391 · PMID 33271806

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In contrast, male flies showed a trend towards increased modification of histone H4 by four weeks of age and a significant increase in 4-HNE modification of all core histones by 6 weeks of age ( Figure 2 E,F).

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