Changes in Motor, Cognitive, and Behavioral Symptoms in Parkinson's Disease and Mild Cognitive Impairment During the COVID-19 Lockdown.

Front Psychiatry · 2020 · PMC7768013 · PMID 33381057

Europe PMC DOI

hedged sentences

0.0660

closest p · 1.3× alpha

0.0860

boldest claim

The sentences

borderline significantp = 0.066so close (0.05 < p ≤ 0.1)

Significant results were found for nighttime behaviors ( p = 0.007), with borderline significant results for depression ( p = 0.066) and aberrant motor behavior ( p = 0.086).

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borderline significancep = 0.086so close (0.05 < p ≤ 0.1)

Regarding MDS-UPDRS Part II, PD-MCI showed significant higher frequencies in speech ( p = 0.020), saliva and drooling ( p = 0.039), turning in bed ( p = 0.006), tremor ( p = 0.012), getting out of bed ( p = 0.001), and walking and balance ( p = 0.003), with borderline significance values for dressing ( p = 0.086) and hygiene ( p = 0.086).

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approached significanceno p-value reported

First, the relatively small sample size of the groups might increase the likelihood of spurious associations and a lack of significance (e.g., the results approached significance for many NPI and MDS-UPDRS items).

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