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Effect of amitriptyline on orthodontic tooth movement in rats: an experimental study.

J Dent Res Dent Clin Dent Prospects · 2020 · PMC7770401 · PMID 33408818

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Accordingly, we expected to find a significantly diminished OTM rate; however, despite the lower mean rate of OTM in the amitriptyline group, it did not reach statistical significance and therefore, our findings could not clarify the anti-inflammatory effects of amitriptyline, keeping in mind that we did not determine the level of inflammatory factors.

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