Barely Significant
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In Situ Remodeling Overrules Bioinspired Scaffold Architecture of Supramolecular Elastomeric Tissue-Engineered Heart Valves.

JACC Basic Transl Sci · 2020 · PMC7775962 · PMID 33426376

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an increasing trendno p-value reported
an overall trendno p-value reported
Although the valves in both groups showed an increasing trend in pressure gradient over time, which was not statistically significant, the aTEHV group showed an overall trend of higher systolic pressure gradients, which might have been caused by the tendency for increased leaflet stiffness in this group.

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showed a trendno p-value reported
The aTEHVs showed a trend of earlier and higher incidence of moderate valve regurgitation in time on TTE ( Figure 2M ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.