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<i>Cyba</i>-deficient mice display an increase in hematopoietic stem cells and an overproduction of immunoglobulins.

Haematologica · 2021 · PMC7776239 · PMID 31919083

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Confirming this hypothesis, CR Cyba -/- mice showed a significant increase in IgA, in IgG, in serum, and a general increase in IgM that did not reach statistical significance ( Figure 8D ).

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