Outcomes after late bone marrow and very early central nervous system relapse of childhood B-acute lymphoblastic leukemia: a report from the Children's Oncology Group phase III study AALL0433.

Haematologica · 2021 · PMC7776266 · PMID 32001530

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0800

boldest claim

The sentences

showed a trendP =0.07so close (0.05 < p ≤ 0.1)

In patients with MRD <0.1% at the end of Induction-1, HCT showed a trend of improved 3-year DFS of 90.7±6.5% versus 74.1±5.8% for chemotherapy ( P =0.07).

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a trend towards significanceP =0.08so close (0.05 < p ≤ 0.1)

When patients on both vincristine dose arms were included, the 3-year DFS maintained a trend towards significance (73.1±5.6% for HCT vs. 65.6±4.0%, P =0.08).

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