Systemic and intestinal porcine epidemic diarrhea virus-specific antibody response and distribution of antibody-secreting cells in experimentally infected conventional pigs.

In contrast, in vitro stimulation of MNCs from PEDV-inoculated pigs significantly enhanced PEDV-specific IgA antibody secretion from MLNs at 28 dpi and the ileum at 7 dpi, and showed a trend towards enhancing secretion from the ileum at 28 dpi (p = 0.057), compared to no stimulation (Figure 4 ).

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p-values of p < 0.10, p < 0.05, and p < 0.01 were considered to be suggestive, significant, and highly significant, respectively, for all comparisons.

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