Similarly, livers from mice lacking PKCβ exhibited a reduction in levels of acylcarnitine (4.22 ± 1.37 PKCβ fl/fl vs 2.89 ± 0.68 pmol/mg protein PKCβ Hep−/− , n = 4, p = 0.18), which did not reach statistical significance.
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Hepatocyte-specific PKCβ deficiency protects against high-fat diet-induced nonalcoholic hepatic steatosis.
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