In accordance with our “in house” results, we observed a significant relationship between the expression of MAFG and survival in our additional large cohort of 1035 patients analyzed from Moffitt Center and in the public database with 984 from TCGA with a clear trend toward higher overall survival when MAFG expression is low.
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MAFG is a potential therapeutic target to restore chemosensitivity in cisplatin-resistant cancer cells by increasing reactive oxygen species.
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