Manual and automated tissue segmentation confirm the impact of thalamus atrophy on cognition in multiple sclerosis: A multicenter study.

Neuroimage Clin · 2021 · PMC7787946 · PMID 33401136

Europe PMC DOI

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closest p · 1.0× alpha

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The sentences

marginally significantp = 0.05actually significant

Compared to CP patients, CI patients had smaller thalami based on all methods, excepted the left thalamus volumes obtained through manual outlining ( p = 0.18) and marginally significant for left thalamus volumes from GIF ( p = 0.05).

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a negative trendno p-value reported

Except for CAT12, a proportional difference with a negative trend was observed in all scatter plots showing the agreement between the automated and manual thalamus volume measurements.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.