Antisense oligonucleotide and adjuvant exercise therapy reverse fatigue in old mice with myotonic dystrophy.

Mol Ther Nucleic Acids · 2021 · PMC7787993 · PMID 33473325

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showed a trendno p-value reported

Moderate-intensity exercise training, a non-pharmacological intervention that reduces chronic fatigue in patients with FSHD, 24 also showed a trend for improvement in fatigue of old HSA LR mice but without correction of the molecular or histologic phenotype.

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