Barely Significant
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Low-pass whole genome bisulfite sequencing of neonatal dried blood spots identifies a role for RUNX1 in Down syndrome DNA methylation profiles.

Hum Mol Genet · 2021 · PMC7788293 · PMID 33001180

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nominally significantp < 0.05actually significant
In contrast to the other comparisons, the DD versus TD comparison only identified 59 nominally significant ( p < 0.05) DMRs (54% hypermethylated, 46% hypomethylated) from 1861 background regions that were assembled from the 25 122 420 CpGs covered in these groups ( Supplementary Material, Table S2C ).

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