Barely Significant
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Alcohol use disorder causes global changes in splicing in the human brain.

Transl Psychiatry · 2021 · PMC7790816 · PMID 33414398

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In NA, HSPA6 mRNA was approximately twofold upregulated, but this difference did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.