Barely Significant
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Effects of spinal manipulative therapy on inflammatory mediators in patients with non-specific low back pain: a non-randomized controlled clinical trial.

Chiropr Man Therap · 2021 · PMC7792327 · PMID 33413508

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SMT-associated differences in change scores in production levels of the studied mediators and SMT-related effect sizes are shown in Table 2 . Relative to their respective baselines, post-SMT levels of TNFα were reduced in both LBP patient groups (%Δ 17–22, Table 2 ) but did not reach statistical significance (Fig. 2 a).

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