Integrated analysis of telomerase enzymatic activity unravels an association with cancer stemness and proliferation.

We then calculated empirical P values by comparing observed correlations with those generated from the random permutation; 27 of 31 cancer types remained highly significant (empirical P values <0.05) (Supplementary Data 5 ).

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EXTEND scores and cell line telomerase activity were significantly correlated (Rho = 0.72, P = 0.01), whereas the correlation for TERT did not reach statistical significance (Rho = 0.55, P = 0.08) (Fig. 1b and Supplementary Fig. 7 ).

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