Among the patients who had undergone transplantation procedure in our center, there was a marginally significant positive correlation between the urine NGAL concentration and the number of donor/recipient HLA mismatches (Spearman R = 0.31; p = 0.049).
Both serum and urine NGAL concentrations on day 2 after transplantation predicted delayed graft function independently of serum creatinine and urine output; however, NGAL as an independent variable did not reach statistical significance in the models predicting graft loss or recipient’s death at 2 or 5 years post-transplant [ 42 ].
On the contrary, we observed a significant increase in eGFR values in the subgroup with final eGFR >90% of baseline eGFR ( p < 0.001; Figure 1 B), resulting in a highly significant difference in final eGFR values between the studied subgroups: median final eGFR was 30 mL/min/1.73 m 2 in patients with final eGFR ≤90% of the baseline values, and 56 mL/min/1.73 m 2 in patients with final eGFR >90% baseline ( p < 0.001).