Ethanol exposure drives colon location specific cell composition changes in a normal colon crypt 3D organoid model.

Sci Rep · 2021 · PMC7801615 · PMID 33432071

Europe PMC DOI

hedged sentences

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closest p · 1.0× alpha

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boldest claim

The sentences

nominally significantP = 0.05actually significant

Of the 1,965 DEGs identified in our pilot study 14 , 749 (38.18%) were at least nominally significant ( P = 0.05) in our larger sample set.

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highly significantno p-value reported

Highly significant genes were selected to be assayed if: they were novel; had been previously associated with alcohol treatment in tissues other than colon 16 ; or previously associated with CRC through genome-wide association studies (GWAS) 1 , 17 , 18 .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.