Evaluation of inflammation and follicle depletion during ovarian ageing in mice.

Sci Rep · 2021 · PMC7801638 · PMID 33432051

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a clear trendno p-value reported

However, we were unable to detect an age-related increase in NLRP3 inflammasome protein levels, though a clear trend was observed for IL-18.

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an overall trendno p-value reported

Initially, we examined the ovarian mRNA expression levels of major pro-inflammatory cytokines Tnfa, Il6, Il1a and Il1b and observed an overall trend towards increasing expression level with increasing age.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.