Ca²⁺ signaling driving pacemaker activity in submucosal interstitial cells of Cajal in the murine colon.

PTCL area was significantly reduced to 78 ± 5.8% ( Figure 13—figure supplement 1G ; n = 4) and although both PTCL count and number were reduced to 75.3 ± 10.5% and 74.8 ± 9.3%, respectively, these effects did not reach statistical significance (PTCL count: p value = 0.08 and PTCL number: p value = 0.06; Figure 13—figure supplement 1H&I ; n = 4).

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