The Genetic Background of Central Serous Chorioretinopathy: A Review on Central Serous Chorioretinopathy Genes.

J Genomics · 2021 · PMC7806452 · PMID 33456587

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marginally significantno p-value reported

CFHrs2298877, MAPK1rs1063311, CFHrs529825 and CFHrs2284664 SNPs were marginally significant in one of the two cohorts and in the joint analysis which could mean a no significant finding clinically.

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showed a trendno p-value reported

The rest of the tested SNPs {rs12144939 (A:G/T, OR=1.33, CI:1.03-1.70, P=0.031), rs3753394 (A:C/T, OR=0.78, CI:0.6-1.0, P=0.027), rs1061170 (A:T/C, OR=0.83, CI:0.66-1.05, P=0.065), rs2284664(A:C/T, OR=1.37, CI:1.07-1.76, P=0.009)} results showed a trend toward association but did not reached the significance threshold 45 .

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