Efficient multiplexed genome engineering with a polycistronic tRNA and CRISPR guide-RNA reveals an important role of detonator in reproduction of Drosophila melanogaster.

PLoS One · 2021 · PMC7808601 · PMID 33444382

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closest p · 4.4× alpha

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failed to reach statistical significancep = 0.22not close (p > 0.1)

We also observed reduced hatching rate for the cross between dtn/7712 and FM7/Y (34%) or the one between dtn/25730 and B/Y (32%) compared to the control crosses between dtn/FM7 (or dtn/B ) and FM7/Y (or B/Y ), although the difference failed to reach statistical significance (p = 0.22 and 0.058, respectively).

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