Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy.

Nat Commun · 2021 · PMC7809039 · PMID 33446657

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showed a trendno p-value reported

The growth of HCT116 xenograft tumours was somewhat sensitive to dietary serine and glycine restriction (as previously shown 7 ) and also showed a trend to a decrease in mice treated with PH755 (Fig. 7c ), consistent with a previous report showing an effect of PH755 on HCT116 tumour growth 24 .

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