A comprehensive analysis of the expression, epigenetic and genetic changes of HNF1B and ECI2 in 122 cases of high-grade serous ovarian carcinoma.

Oncol Lett · 2021 · PMC7816296 · PMID 33574924

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0.0560

closest p · 1.1× alpha

0.0560

boldest claim

The sentences

marginally non-significantP=0.056so close (0.05 < p ≤ 0.1)

Association of HNF1B promoter methylation with protein expression was marginally non-significant (Z=1.91, N=67, P=0.056).

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reached borderline significanceno p-value reported

The SNP rs757210 was found to be associated with promoter methylation in high-grade serous carcinoma (HGSC), and its involvement also reached borderline significance in ovarian clear cell carcinoma (OCCC) ( 5 ).

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