Apolipoprotein L1 risk genotypes in Ghanaian patients with systemic lupus erythematosus: a prospective cohort study.

Lupus Sci Med · 2021 · PMC7816898 · PMID 33461980

Europe PMC DOI

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closest p · 2.0× alpha

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The sentences

did not reach statistical significancep=0.1so close (0.05 < p ≤ 0.1)

APOL1 high-risk (2RV) patients exhibited numerically higher SDI, compared with patients with zero or one variant, although this did not reach statistical significance (mean SDI 0RV or 1RV=0.99±1.2 vs 2RV=1.75±2.6, p=0.1).

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may be significantno p-value reported

Importantly, the APOL1 risk genotype correlated with SDI, renal progression and case fatality independent of SLE disease activity, suggesting that in Ghanaian patients with SLE, these variants may be significant prognostic indicators.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.