The Parkinson's disease-associated gene ITPKB protects against α-synuclein aggregation by regulating ER-to-mitochondria calcium release.

Proc Natl Acad Sci U S A · 2021 · PMC7817155 · PMID 33443159

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a strong trendno p-value reported

Mice injected with ΔGSS hITPKB-Flag AAV exhibited a strong trend toward reduced insoluble pS129 α-syn levels compared to control mice injected with GFP AAV ( SI Appendix , Fig.

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