Comparative host transcriptome in response to pathogenic fungi identifies common and species-specific transcriptional antifungal host response pathways.

Comput Struct Biotechnol J · 2021 · PMC7817431 · PMID 33510868

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Patients carrying the C allele showed a trend towards increased IL-1β and decreased IL-1Ra BAL levels compared to carriers of the homozygous reference TT genotype ( Fig. 5 D) suggesting that this polymorphism (rs5744174) influences pulmonary inflammation during aspergillosis.

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