The area of CD68-positive cells was smaller following treatment but did not reach statistical significance (Fig. 2 a, c; 0.010 ± 0.0021 mm 2 [saline, n = 8] versus 0.0053 ± 0.0011 mm 2 [EC2319, n = 9], P = 0.093).
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Efficacy and tolerability of folate-aminopterin therapy in a rat focal model of multiple sclerosis.
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