Analysis of EBV (+) GC (n = 27) revealed that PD-L1 expression in EBV (+) GC correlated positively with CD8 + lymphocyte infiltration, although the result did not reach statistical significance (probably due to the small number of samples in the FMU cohort) (Fig. 1 d).
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PD-L1 overexpression in EBV-positive gastric cancer is caused by unique genomic or epigenomic mechanisms.
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