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Targeting G1/S phase cell-cycle genomic alterations and accompanying co-alterations with individualized CDK4/6 inhibitor-based regimens.

JCI Insight · 2021 · PMC7821594 · PMID 33427211

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Second, while PFS and clinical benefit rate were improved with a greater degree of matching, survival changes did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.