marginally significantP = 0.06
6A ) and running exerted a marginally significant inhibitory effect ( P = 0.06 for main effect of running), but there was no significant interaction effect ( P = 0.86).
6A ) and running exerted a marginally significant inhibitory effect ( P = 0.06 for main effect of running), but there was no significant interaction effect ( P = 0.86).
4B ), but the effects did not reach statistical significance ( P = 0.09 for running main effect; P = 0.11 for clodronate main effect; P = .66 for interaction effect).
Mice in the wheel running-only group also appeared to exhibit a decrease in Adgre1 expression, albeit smaller, but neither the main effect of running nor the interaction with clodronate were significant ( P = 0.22 and P = 0.43, respectively; the simplest unadjusted two-group comparison with control mice also failed to reach significance with P = 0.11).