Barely Significant
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Interim Results of a Phase 1-2a Trial of Ad26.COV2.S Covid-19 Vaccine.

N Engl J Med · 2021 · PMC7821985 · PMID 33440088

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a clear trendno p-value reported
After the administration of the first dose, a trend toward a higher incidence of solicited systemic adverse events was noted with the higher vaccine dose, and a clear trend for decreasing grade 3 adverse events with increasing age was observed.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.