Impact of Genetic Factors on the Age of Onset for Type 2 Diabetes Mellitus in Addition to the Conventional Risk Factors.

J Pers Med · 2020 · PMC7822179 · PMID 33375163

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a significant trendno p-value reported

There is a significant trend between GRS and the age of onset groups for T2DM in the total Case population and also by sex.

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a decreasing trendno p-value reported

The “weight” of the non-genetic factors is increasing with the progression of T2DM; however, since the genetic component never changes, there is a decreasing trend in the share of genetic risk factors (see more details in Figure 4 ). 3.9.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.