Barely Significant
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Decrease in Myelin-Associated Lipids Precedes Neuronal Loss and Glial Activation in the CNS of the Sandhoff Mouse as Determined by Metabolomics.

Metabolites · 2020 · PMC7823728 · PMID 33396723

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clearly significantno p-value reported
One possibility is that the decreased abundance of myelin lipid components, clearly significant at the earliest time points, reflects impaired biosynthesis of the lipid components of myelin rather than myelin destruction.

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