For both 5FU-loaded stent types there was a clear trend of concentration-dependent reduction of cell viability following 72 h of exposure, with statistically significant differences observed between the stent-released 5FU concentrations and the non-treated (media) or drug-free (blank) controls ( Figure 9 ).
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Development and In Vitro Evaluation of 5-Fluorouracil-Eluting Stents for the Treatment of Colorectal Cancer and Cancer-Related Obstruction.
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