Effect of Tiotropium Soft Mist Inhalers on Dynamic Changes in Lung Mechanics of Patients with Chronic Obstructive Pulmonary Disease Receiving Mechanical Ventilation: A Prospective Pilot Study.

Pharmaceutics · 2020 · PMC7824634 · PMID 33396552

Europe PMC DOI

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did not reach statistical significanceno p-value reported

In our study, although inter-time-point differences in the parameters of lung mechanics did not reach statistical significance, we observed trends of a decrease in PIP, Pmean, and Pplat at 1 h, 3 h, and 6 h after two SMI administrations compared with the baseline values.

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