Although it was not the main aim of this study (i.e., underpowered to robustly detect effects on HOMA-IR), we nevertheless observed that BCAA restriction was associated with a decrease in HOMA-IR levels in healthy subjects assigned to the BCAA-restricted diet over seven days, with a p -value approaching significance.
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A Novel Dietary Intervention Reduces Circulatory Branched-Chain Amino Acids by 50%: A Pilot Study of Relevance for Obesity and Diabetes.
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